Advancing perinatal mental
health and well-being: The
DC Mother-Infant Behavioral
Wellness Program
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Helping D.C. babies enjoy the strongest start at life

For a staggering number of women, pregnancy is not a time of joy. Women often struggle with stress, depression and anxiety during pregnancy, and this maternal mental health distress can persist a year after giving birth. According to the Centers for Disease Control and Prevention, rates of depression among new moms increased seven-fold from 2000 to 2015. Twice as many low-income African American women experience maternal mental distress (stress, depression anxiety), and the health disparity has been magnified by the COVID-19 pandemic. Experiencing mental health concerns can lead to negative effects on health for both mother and her baby and changes the infant’s developing brain in worrisome ways.

Yet low-income Black women are less likely to receive screening or have available treatment during this critical period - especially in the District of Columbia. Even when stress, anxiety or depression are identified, many women are not adequately treated because they face obstacles daily in life and distrust healthcare providers or the system. Fortunately, we have the tools to effectively find and treat these women, and intervening early can help D.C. babies enjoy the strongest start at life.

On March 16, 2021, the Patient-Centered Outcomes Research Institute (PCORI) Board of Governors approved for a total of $42.7 million in new funding. PCORI’s three-year, $4.2 million grant to the Developing Brain Institute supports maternal mental health research and address racial disparities. Catherine Limperopoulos, Ph.D., Chief & Director of the Developing Brain Institute, and Huynh-Nhu (Mimi) Le, Ph.D., a Professor in the George Washington University’s Department of Psychological and Brain Sciences, are co-Principal Investigators for the study, “Advancing perinatal mental health and well-being: The DC Mother-Infant Behavioral Wellness Program.”

Contact us to learn more about this PCORI-funded research project
+1 202.476.3842

Read the PCORI news release

Read the Children’s National news release

Now Hiring | Perinatal Behavioral Health Specialist

The Perinatal Behavioral Health Specialist will provide behavioral health screening and appropriate response, including behavioral health interventions, to pregnant and postpartum patients; will collaborate with all involved teams and support services to ensure that patients’ and families’ needs are met; will identify and prioritize clinical and psychosocial goals; will problem solve to ensure follow through on needed responses by the multidisciplinary team; will ensure optimal outpatient coordination, and excellent collaboration between teams and partner organizations with a focus on patient experience and outcomes. The Perinatal Behavioral Health Specialist also will provide support and guidance to partner organizations. The Perinatal Behavioral Health Specialist will play a unique role in supporting women through pregnancy and into the early postnatal period.
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Now Hiring | Patient Navigator (2)

The Patient Navigators will foster positive and professional interpersonal relationships with patients, families, physicians, hospital staff, community agency representatives and visitors. These individuals will promote access to care and appropriate utilization of hospital and community services, provide screening interviews for identified patients and, based on findings, facilitate interventions. Successful candidates will identify hospital and community resources to facilitate patient and family coping and will assist families in utilizing these services. The Patient Navigators will function as resources and advocate for Black and African American pregnant and postpartum women with young infants aged up to 12 months in the Washington, D.C. area.
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Now Hiring | Clinical Research Coordinator

The Clinical Research Coordinator participates in or leads day-to-day operations of clinical research studies conducted by the co-Principal Investigators. This individual performs a variety of duties involved in the collection, compilation, documentation and analysis of clinical research data. The successful candidate will attain progressive functional knowledge of Good Clinical Practices, Office of Human Research Protections regulations and Food and Drug Administration regulations, when applicable.
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Stakeholder engagement

The DC Mother-Infant Behavioral Wellness Program, like other projects funded by PCORI, will meaningfully involve patients, clinicians and other healthcare stakeholders while the study is being planned, conducted and when research results are shared with the public. This study has three external advisory boards, the Local Advisory Board, National Advisory Board and Stakeholder Engagement Core.

  • We’ll track health - including mental health - of moms starting during pregnancy and will monitor how their newborns develop.


Our overall goal is to partner with former patients, moms with experience giving birth in D.C., and other members of low-income Black communities to develop and test different approaches to overcome obstacles and achieve health equity by providing effective mental health screening and care. We have two major aims. First, we want to personalize plans that combine patient navigation and a culturally adapted cognitive-behavioral intervention for low-income Black pregnant women designed to boost recruitment and retention within the healthcare system.

Second, our prospective randomized controlled study design will help women in two ways, comparing usual care with care guided by a patient navigator that includes culturally adapted cognitive-behavioral interventions and peer support. Women get to choose the type of support that best fits their lifestyle, virtual or in person.

Our patient partners spoke loudly and clearly: It’s too difficult to get mental health care in D.C., and it ends too quickly. So, participants will remain in the study up to 12 months after delivery. And our study also will include women who do not yet meet criteria for being diagnosed with major depression or anxiety. #NoMotherLeftBehind.


Our diverse team will include patients; community leaders; midwives and doctors who treat women during pregnancy and their infants after birth; psychologists; and advisers skilled at transforming health care to better meet patient’s unique needs, ensuring insurance covers it and ramping up software so it can be used by more people nationwide.