Subechhya Pradhan, Ph.D.

Research Faculty (Asst. Prof)

Subechhya Pradhan, Ph.D., is research faculty in the Developing Brain Institute at Children’s National and Assistant Professor of Pediatrics and Radiology at the George Washington University. Dr. Pradhan received her doctoral degree from Vanderbilt University and joined the Institute after finishing postdoctoral training at Johns Hopkins University where she worked on implementing and optimizing novel pulse sequences for measuring neurochemicals in the brain. Dr. Pradhan’s current projects include study of metabolic profiles in the fetal and neonatal brain as well as the placenta to ultimately aid clinicians to assess and monitor high-risk fetuses during pregnancy and neonates during the early postnatal period.

Address: 111 Michigan Ave NW, Washington, DC 20010
Email: fetalbrain@childrensnational.org
Department: MRI Lab

Recent Publications & Presentations

Basu SK, Pradhan S, Barnett SD, Mikkelsen M, Kapse KJ, Murnick J, Quistorff JL, Lopez CA, du Plessis AJ, Limperopoulos C
Regional differences in gamma-aminobutyric acid and glutamate concentrations in the healthy newborn brain AJNR Am J Neuroradiol. 2022 Jan;43(1):125-131. doi: 10.3174/ajnr.A7336. Epub 2021 Nov 11. PMID: 34764083 https://pubmed.ncbi.nlm.nih.gov/34764083/
Pradhan S, Niforatos-Andescavage N, Saeed H, Barnett S, Kapse K, Andersen N, Quistorff J, Lopez C, Vezina G, Limperopoulos C Impaired fetal brain metabolism in pregnancies complicated by elevated maternal stress during the COVID-19 pandemic. Poster presentation. Pediatric Academic Societies 2021 Virtual Meeting, May 2, 2021.
Basu S, Espinosa K, Pradhan S, Kapse K, De-Asis Cruz J, Kapse A, Norman S, Fischer D, Andescavage N, Limperopoulos C Cerebellar structure, function and neurodevelopmental outcomes in very preterm infants. Poster presentation. Pediatric Academic Societies 2021 Virtual Meeting, April 30, 2021.
Pradhan S, Kapse K, Niforatos-Andescavage N, Quistorff J, Lopez C, Limperopoulos C. Increased brain lactate in fetuses of pregnant women with diabetes. Poster presentation. Pediatric Academic Societies 2021 Virtual Meeting, April 30, 2021.
Basu SK, Pradhan S, Jacobs MB, Said M, Kapse K, Murnick J, Whitehead M, Chang T, du Plessis A, Limperopoulos C.
Age and sex influences gamma-aminobutyric acid concentrations in the developing brain of very premature infants.
Scientific Reports. 2020;10(1):10549. Published 2020 Jun 29. doi:10.1038/s41598-020-67188-y https://pubmed.ncbi.nlm.nih.gov/32601466/
Pradhan S, Kapse K, Jacobs M, Niforatos Andescavage N, Quistorff JL, Lopez C, Bannatine KL, Reinholdt Andersen N, Vezina G, Limperopoulos C.
Non-invasive measurement of biochemical profiles in the healthy fetal brain
[published online ahead of print, 2020 Jun 8]. Neuroimage. 2020;219:117016. doi:10.1016/j.neuroimage.2020.117016 https://pubmed.ncbi.nlm.nih.gov/32526384/
Wu Y, Lu YC, Jacobs M, Pradhan S, Kapse K, Zhao L, Andescavage N, Vezina G, du Plessis A, Limperopoulos C.
Association of prenatal maternal psychological distress with fetal brain growth, metabolism, and cortical maturation.
JAMA Network Open. 2020 Jan 3;3(1):e1919940. doi: 10.1001/jamanetworkopen.2019.19940. PMC6991285 https://pubmed.ncbi.nlm.nih.gov/31995213/
Basu S, Pradhan S, Kapse K, McCarter R, Murnick J, Chang T, Limperopoulos C.
Third trimester cerebellar metabolite concentrations are decreased in very premature infants with structural injury.
Scientific Reports. 2019 Feb 4;9(1):1212. doi: 10.1038/s41598-018-37203-4. Link: pubmed.ncbi.nlm.nih.gov/30718546/ https://pubmed.ncbi.nlm.nih.gov/30718546/
Krishnan A, Tague L, Rudra H, Pradhan S, Vezina G, Limperopoulos C.
Clinical course of a fetus with hypoplastic left heart syndrome and premature ductal constriction.
Cardiol Young. 2018 Dec 27:1-3. doi: 10.1017/S1047951118001701. [Epub ahead of print] https://pubmed.ncbi.nlm.nih.gov/30587271/