Sarah B. Mulkey, M.D., Ph.D.

Prenatal-neonatal neurologist

Sarah Mulkey, M.D., Ph.D., is a prenatal-neonatal neurologist in the Division of Fetal and Transitional Medicine at Children’s National Hospital and an assistant professor of Neurology and Pediatrics at the George Washington University School of Medicine & Health Sciences, Washington, D.C. Dr. Mulkey is also the clinical director of the Fetal-Neonatal Neurology Fellowship. She joined Children’s National and the Prenatal Pediatrics Institute in 2016. She grew up in South Florida and earned a BS degree in Chemistry from Florida Atlantic University in 2001 and an M.D. from the Florida State University College of Medicine in 2005. Dr. Mulkey completed a residency in child neurology at the University of Arkansas for Medical Sciences in Little Rock, Arkansas. In 2015, Dr. Mulkey earned a Ph.D. in Clinical and Translational Sciences from the University of Arkansas for Medical Sciences’ Graduate School. Her research interests include brain injury in the fetus and newborn, brain growth and development, and neurodevelopmental outcomes in newborns at risk for brain injury.

Dr. Mulkey has developed national and international expertise in Congenital Zika Syndrome. She co-directs the Congenital Infection Program at Children’s National with Dr. Roberta L. DeBiasi, M.D., MS, chief of Pediatric Infectious Diseases. Dr. Mulkey leads an international multi-site study following neurodevelopmental outcomes of children with antenatal Zika exposure. She provides technical expertise to the Centers for Disease Control’s Zika studies and has contributed to national guidelines for the care of Zika-exposed infants. Dr. Mulkey is also the co-chair of the World Health Organization IPD-MA Outcomes working group. Her research in this area has focused on neuroimaging and long-term neurodevelopment of infants exposed to Zika virus infection in utero.

Dr. Mulkey is an active member of the Society for Pediatric Research and the Child Neurology Society. Her clinical expertise and interests focus on abnormal development of or injury to the developing brain. She has authored multiple peer-reviewed manuscripts on topics related to newborn brain injury, neuroimaging of the newborn brain, autonomic nervous system development, congenital infections and neurodevelopmental outcomes.

Address: 111 Michigan Ave NW, Washington, DC 20010
Email: fetalbrain@childrensnational.org
Department: MRI Lab

Recent Publications & Presentations

Schlatterer SD, Govindan RB, Murnick J, Barnett SD, Lopez C, Donofrio MT, Mulkey SB, Limperopoulos C, du Plessis AJ
In infants with congenital heart disease autonomic dysfunction is associated with pre-operative brain injury Pediatr Res. 2021 Dec 28. doi: 10.1038/s41390-021-01931-7. Epub ahead of print. PMID: 34963700 https://pubmed.ncbi.nlm.nih.gov/34963700/
Schlatterer SD, Govindan RB, Murnick J, Barnett SD, Lopez C, Al-Shargabi T, Donofrio MT, Mulkey SB, Limperopoulos C, du Plessis AJ. Early heart rate variability correlates with pre-operative brain injury score in infants with congenital heart disease. Poster presentation. Pediatric Academic Societies 2021 Virtual Meeting, April 30, 2021.
Schlatterer SD, Sanapo L, du Plessis AJ, Whitehead MT, Mulkey SB.
The Role of Fetal MRI for Suspected Anomalies of the Posterior Fossa.
Pediatr Neurol. 2021 Apr;117:10-18. doi: 10.1016/j.pediatrneurol.2021.01.002. Epub 2021 Jan 10. PMID: 33607354. https://pubmed.ncbi.nlm.nih.gov/33607354/
Whitehead MT, Vezina G, Schlatterer SD, Mulkey SB, du Plessis AJ.
Taenia-tela choroidea complex and choroid plexus location help distinguish Dandy-Walker malformation and Blake pouch cysts.
Pediatr Radiol. 2021 Mar 30. doi: 10.1007/s00247-021-04991-3. Epub ahead of print. PMID: 33783580. https://pubmed.ncbi.nlm.nih.gov/33783580/
Mulkey SB, Hitchings L, Persaud R, Kota S, Maxwell GL, Baker R, du Plessis A, Govindan R.
Cerebral cortical autonomic connectivity in low-risk term newborns.
Clin Auton Res. 2021 Mar 14. doi: 10.1007/s10286-021-00793-7. Epub ahead of print. PMID: 33718981. https://pubmed.ncbi.nlm.nih.gov/33718981/
Schlatterer SD, Govindan RB, Barnett SD, Al-Shargabi T, Reich DA, Iyer S, Hitchings L, Larry Maxwell G, Baker R, du Plessis AJ, Mulkey SB.
Autonomic development in preterm infants is associated with morbidity of prematurity.
Pediatr Res. 2021 Mar 2:1–7. doi: 10.1038/s41390-021-01420-x. Epub ahead of print. PMID: 33654284; PMCID: PMC7922721. https://pubmed.ncbi.nlm.nih.gov/33654284/
Mulkey SB, Polglase GR.
Cerebral oxygen saturation-a useful bedside vital sign for neonatal encephalopathy.
. J Perinatol. 2021 Feb 5. doi: 10.1038/s41372-021-00916-y. Epub ahead of print. PMID: 33547404. https://pubmed.ncbi.nlm.nih.gov/33547404/
Askenazi DJ, Heagerty PJ, Schmicker RH, Brophy P, Juul SE, Goldstein SL, Hingorani S; PENUT Trial Consortium.
The Impact of Erythropoietin on Short- and Long-Term Kidney-Related Outcomes in Neonates of Extremely Low Gestational Age. Results of a Multicenter, Double-Blind, Placebo-Controlled Randomized Clinical Trial.
J Pediatr. 2021 Jan 20:S0022-3476(21)00065-2. doi: 10.1016/j.jpeds.2021.01.031. Epub ahead of print. PMID: 33484699. https://pubmed.ncbi.nlm.nih.gov/33484699/
Mercado M, Daza M, Moore CA, Valencia D, Rico A, Álvarez-Diaz DA, Brault AC, Fitzpatrick K, Mulkey SB.
Discordant Clinical Outcomes in a Monozygotic Dichorionic-Diamniotic Twin Pregnancy with Probable Zika Virus Exposure.
Case Report. Trop Med Infect Dis. 2020 Dec 19;5(4):188. doi: 10.3390/tropicalmed5040188. PMID: 33352748; PMCID: PMC7768539. https://pubmed.ncbi.nlm.nih.gov/33352748/
Mulkey SB.
Head Circumference as a Measure of In Utero Zika Virus Exposure and Outcomes.
JAMA Netw Open. 2020 Jul 1;3(7):e209461. doi: 10.1001/jamanetworkopen.2020.9461. PMID: 32633761. https://pubmed.ncbi.nlm.nih.gov/32633761/
Mulkey SB, DeBiasi RL.
Do Not Judge a Book by Its Cover: Critical Need for Longitudinal Neurodevelopmental Assessment of In Utero Zika-Exposed Children.
Am J Trop Med Hyg. 2020 May;102(5):913-914. doi: 10.4269/ajtmh.20-0197. PMID: 32274991; PMCID: PMC7204577. https://pubmed.ncbi.nlm.nih.gov/32274991/
Wu YW, Goodman AM, Chang T, Mulkey SB, Gonzalez FF, Mayock DE, Juul SE, Mathur AM, Van Meurs K, McKinstry RC, Redline RW.
Do Placental pathology and neonatal brain MRI in a randomized trial of erythropoietin for hypoxic-ischemic encephalopathy.
Pediatr Res. 2020 Apr;87(5):879-884. doi: 10.1038/s41390-019-0493-6. Epub 2019 Jul 1. PMID: 31261373. https://pubmed.ncbi.nlm.nih.gov/31261373/
Mulkey SB, Govindan R, Metzler M, Swisher CB, Hitchings L, Wang Y, Baker R, Larry Maxwell G, Krishnan A, du Plessis AJ.
Heart rate variability is depressed in the early transitional period for newborns with complex congenital heart disease.
Clin Auton Res. 2020 Apr;30(2):165-172. doi: 10.1007/s10286-019-00616-w. Epub 2019 Jun 25. PMID: 31240423; PMCID: PMC6930356. https://pubmed.ncbi.nlm.nih.gov/31240423/
Mulkey SB, Arroyave-Wessel M, Peyton C, Bulas DI, Fourzali Y, Jiang J, Russo S, McCarter R, Msall ME, du Plessis AJ, DeBiasi RL, Cure C.
Neurodevelopmental Abnormalities in Children With In Utero Zika Virus Exposure Without Congenital Zika Syndrome.
JAMA Pediatr. 2020 Mar 1;174(3):269-276. doi: 10.1001/jamapediatrics.2019.5204. Erratum in: JAMA Pediatr. 2020 Mar 1;174(3):305. PMID: 31904798; PMCID: PMC6990858. https://pubmed.ncbi.nlm.nih.gov/31904798/
Juul SE, Comstock BA, Wadhawan R, Mayock DE, Courtney SE, Robinson T, Ahmad KA, Bendel-Stenzel E, Baserga M, LaGamma EF, Downey LC, Rao R, Fahim N, Lampland A, Frantz Iii ID, Khan JY, Weiss M, Gilmore MM, Ohls RK, Srinivasan N, Perez JE, McKay V, Vu PT, Lowe J, Kuban K, O'Shea TM, Hartman AL, Heagerty PJ; PENUT Trial Consortium.
A Randomized Trial of Erythropoietin for Neuroprotection in Preterm Infants.
N Engl J Med. 2020 Jan 16;382(3):233-243. doi: 10.1056/NEJMoa1907423. PMID: 31940698; PMCID: PMC7060076. https://pubmed.ncbi.nlm.nih.gov/31940698/